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B-cell depletion does not prevent complete remission in hepatocellular carcinoma

The tension between cellular and humoral immunity

A clinical case reported by medonline.at suggests that previous B-cell depletion caused by medications like Rituximab does not necessarily prevent immune checkpoint inhibitors from achieving complete remission in patients with inoperable hepatocellular carcinoma, challenging assumptions about the necessity of humoral immunity in these treatments. Can the depletion of B-cells—the primary drivers of the body’s humoral … Weiterlesen …