Nanobody repairs CFTR defect in 90% of cystic fibrosis patients by stabilizing misfolded protein
Researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and Charité – Universitätsmedizin Berlin have developed a nanobody that repairs the defective CFTR protein causing cystic fibrosis in approximately 90 percent of patients. How the nanobody corrects the CFTR defect The nanobody, a tiny antibody fragment, enters human cells and stabilizes the misfolded CFTR protein at position … Weiterlesen …